Two police officers are in hospital after an attempted arrest ended in a “huge” explosion that flattened buildings on a rural property about 80 kilometres from Ballarat.
Specialist Operations Group officers and local detectives attempted to arrest the man at his home on Hamilton Highway, Derrinallum, about 7pm Friday.
He was wanted in relation to a violent incident that happened earlier in the week.
Sergeant Kris Hamilton said the man started acting irrationally and threatened self harm during the attempted arrest.
Police negotiators were called in, who established contact with the man and spoke to him for several hours.
An explosion then occurred at the property about 1.30am.
An Ambulance Victoria spokesman said one of the officers received head injuries and was airlifted to The Alfred hospital in a critical but stable condition.
The second officer was taken by ambulance to Geelong Hospital to be treated for bruising, cuts and abrasions.
The man’s condition remains unknown, but police suspect he died in the blast.
A local resident familiar with the situation said the ‘‘huge’’ explosion had destroyed a house, a large workshop and a shed.
The resident told Fairfax Media that Derrinallum locals had been aware of small explosions happening at the property over the past 12 months, and that a situation there had been "coming to a head".
Police, including bomb squad members, are at the scene and believe there may be other explosive devices at the property.
The Hamilton Highway is closed between Camperdown-Lismore Road and Darlington Road.
More from the scene at #Derrinallum where two police members were injured in an explosion last night pic.twitter.com/TbyrscuzNq
— 7NewsMelbourne (@7NewsMelbourne) April 12, 2014
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