A FIFTEEN-year-old girl was robbed at knifepoint while working her first shift at a Sturt Street pharmacy, with one robber saying 'nice doing business with you' after threatening her with the blade.

The County Court at Ballarat on Tuesday heard Craig Kemp, 42, and Brendan Collins, 21, both of Ballarat, had earlier cased the Priceline Pharmacy about 6pm on December 1 last year, moving their car to the back of the store before returning about 6.30pm to rob it.

Crown prosecutor Pat Bourke told the court Kemp, armed with a knife, became angry with the young employee after she couldn't open the cash register.

"He became frustrated with the delay and said to her 'don't f*** me around girl, it shouldn't be taking this long, get it open',"Mr Bourke said.

"Once the register was opened, the accused leaned forward and scooped up handfuls of notes from the till and ran from the building with Collins.

"Before leaving the store he turned to the victim and said 'nice doing business with you'."

The court heard the men fled the the scene in a green Subaru station wagon and continued to break in and rob several more Ballarat businesses.

The prosecutor said they broke into Ivy Hair in Doveton Street North, stealing $350 worth of hair products before breaking into the Glos Nailbar in Pleasant Street South and stealing the till containing about $400.

Continuing the brazen crime spree, the court heard the men the attempted to break into a Macarthur Street business before attending BWS Liquor in Wendouree and stealing two slabs of mixed drinks.

Kemp and Collins on Tuesday pleaded guilty to charges including armed robbery, burglary, theft and attempted burglary.

Kemp also pleaded guilty to reckless conduct endangering a person and dangerous driving while being pursued by police, relating to a police chase on December 2 in which he sped away from a breath testing site before crashing into a fence in Wendouree.

The pair are expected to be sentenced by County Court Judge Bill Stuart on Wednesday.