Victoria's coronavirus tally has risen to 466 as Premier Daniel Andrews begs people to stay home.
Stage two of national shutdowns were declared on Tuesday night by Prime Minister Scott Morrison.
On Wednesday morning, Mr Andrews backed the further closures and crackdown on social functions.
"No parties, no outings, no gatherings. There's just no, no excuse," Mr Andrews told reporters in Melbourne.
"If you can stay at home, you must stay at home. It is very, very simple.
"You should not be having friends over for a dinner party; you should not be going out shopping unless you need to.
"Kids on school holidays cannot be having friends over."
The Victorian coronavirus tally grew by 55 overnight to 466 cases.
On Tuesday it was confirmed two Victorians are in intensive care because of the virus.
Mr Andrews implored people to realise that overseas, otherwise healthy people have died from COVID-19, which is why isolating is so important to stop the spread.
"There's a lot of talk that this is the greatest risk for those who are frail and aged," he said.
"Yes, it is, but no-one should kid themselves that otherwise healthy people in their 40s, perhaps even younger, haven't died from this."
About 500 police officers will have the daily task of enforcing the closure of non-essential services in Victoria and the mandatory 14-day self-isolation for travellers.
See the premier's full statement here.
Individuals face fines of up to $25,000 and business could be forced to cough up $100,000 for breaching restrictions.
An expanded list of businesses will be forced to close their doors at midnight on Wednesday with an emphasis on stopping large gatherings.
Weddings will be restricted to the couple, celebrant and two witnesses only, while funerals can only have a maximum of 10 mourners.
Open house inspections and auctions are banned as are personal services such as beauty therapy, waxing, tattoo parlours and massage to go with the closure of pubs, clubs, cafes and restaurants announced on Sunday.
Watch the premier's press conference here.
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LATEST NATIONAL (STAGE TWO) CORONAVIRUS RULES
* From midnight on Wednesday food courts in shopping centres will only be available for takeaway food.
* Auctions and open house inspections are banned.
* Outdoor and indoor markets are banned while rules around major food markets will be addressed by states and territories.
* Personal services such as beauty therapy and tattoo parlours (but not physiotherapy) are banned.
* Hairdressers and barbers can continue but must strictly manage social distancing and restrict the amount of time a patron can be in the premises to no more than 30 minutes.
* Amusement parks and arcades, and indoor and outdoor play centres must close.
* Boot camps and personal training must be limited to 10 peoeple.
* Galleries, museums, libraries and swimming pools must close.
* Weddings can continue to be conducted where it is just the couple the celebrant and two witnesses, no more than five people.
* Funerals are limited to no more than 10 people.
* It is safe to send children to school up to the end of the term.
* But some pupil-free days will be needed to plan distance learning.
* Schools will reopen after the term break with a mix of distance learning and in-school learning for all "essential workers".
* PM to meet with teachers and other sector representatives about keeping schools open and protecting staff.
* Everyone who still has a job is an essential worker.
* The official "do no travel" warning will turn into an outright ban on overseas travel, with some exceptions such as aid workers and compassionate travel.
* New offence of profiteering and seeking to export goods overseas, relating to such things as medical supplies and masks.