Victoria Police has confirmed a cyclist was killed after being struck by a car this morning.

Police investigators believe the male cyclist, in his 50s, was struck by a car on the Midland Highway at Eganstown about 9.55am.

Paramedics were called but the cyclist died at the scene.

The driver of the car, an 81-year-old man from Newlyn, stopped at the scene and is assisting police.

The Midland Highway remains closed in both directions.

The Major Collision Investigation Unit is now at the scene.

It comes after a male driver died after his car left the Daylesford-Ballan Road at Koorweinguboora yesterday afternoon.

The Hepburn community has been rocked by a number of lives lost on its roads this year.

Anyone who witnessed the collision, has dash cam footage or any other information that could assist police with their enquiries is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au

EARLIER:

THE Midland Highway remains closed at Eganstown following a crash earlier this morning.

The incident occurred on the highway, between Blampied and Daylesford, just before 10am this morning.

Ambulance Victoria confirmed they were called to reports of a crash between a car and bike rider at 9.55am.

The road is closed in both directions on the Midland Highway near Deep Spring Road. Police are directing Daylesford-bound traffic via an alternate route from Blampied.

Emergency services remain at the scene.

The Courier understands Victoria Police's Major Collisions Investigation Unit is en route.

More to come.