UPDATE: Liam Oliver's father Darren said Dianne Coburn had made contact and would go and look for the boys on Tuesday.
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"We're a lot more optimistic now," he said.
"My wife's sister (Dianne Coburn) made contact and said where the boys were was not as badly affected."
"She's getting a bus over there on Tuesday and will hopefully bump into the boys."
UPDATE: Four members of the same family are missing in the Tsum Valley.
Francis and Jen Comber are travelling with their two young daughters Rani and Neve.
Mr Comber's mother Dianne Comber said they were waiting on any news of the family.
"They were trekking in the Tsum Valley, in the earthquake area," she said.
"No one's heard anything from them yet."
The family is on a long trip through Asia, leaving Australia in June last year.
Liam Oliver, 18, was travelling with his aunt Dianne Coburn further North in the Annapurna Valley when the quake hit.
Both are listed missing on the Red Cross's Family Links site, on which people can log in and let others know they are alive.
His brother Darcy confirmed to Fairfax Media he was missing but declined to comment.
He posted on Twitter on Sunday morning that Liam had been travelling the Annapurna Circuit, a popular trek.
The teen attended Daylesford Secondary College and lists cafe Moor Please as his employer on Facebook.
More than 1800 people are estimated dead and an increasing number of Australians are missing following the disaster.