The Andrews government has approved plans for Ormond's first high-rise - a 233-apartment tower above the station on North Road - that is set to dwarf surrounding buildings.

It was opposed by local residents and Glen Eira Council, which pushed for an eight-storey building in the low-rise area.

But the 13-storey development was approved by a planning panel in March and supported by Planning Minister Richard Wynne.

In order for the tower to go ahead, changes to the Glen Eira planning scheme needed to pass both houses of Parliament.

However, the project now appears to be hanging in the balance, as the opposition prepares to block the project in the upper house on Wednesday, with the Greens signalling they will support the move.

If the government's proposed amendment is successfully revoked, it will take the project back to the drawing board, potentially unravelling an extensive planning process. Stopping a project in this way has been described by planning experts as exceptionally rare.

Greens planning spokeswoman Samantha Dunn said the government needed to come up with a design that meets community expectations and has called for the building to be reduced to eight storeys.

Opposition public transport spokesman David Davis said the tower was an example of inappropriate planning.

"The opposition is deeply concerned with the government's approach to its massive and inappropriate tower in the local Ormond shopping centre," said Mr Davis.

"The opposition supports sensible transport orientated development, but does not support riding roughshod over local communities as occurred in Ormond."

Mr Davis has also flagged another revocation motion of the controversial Markham Estate - 1.4 hectares of prime Ashburton land the Andrews government wants to develop for both private and public housing.

The Greens have also signalled that they would support this.

The Property Council of Australia has hit out at the both the Liberals and the Greens, with executive director of the Victorian branch Sally Capp??? accusing the parties of creating uncertainty around the projects to benefit their own political purposes.

"This is not a political game," she said.

"We are disappointed, concerned and frustrated. One of the main things that really drives affordability and supply of housing is planning certainty and these motions against Ormond Station and Markham Estate ... will throw everything up in the air."

She said the project was a "poster child" for urban property development "at a time when we absolutely have to address more housing supply in the middle ring".

Mr Davis' moves to oppose the projects come despite Opposition Leader Matthew Guy approving thousands of apartments in Melbourne's CBD when he was planning minister - including in what he claimed was the first 100-storey building in the southern hemisphere - earning him the moniker "My Skyscraper".

In 2014, he approved a 31-storey tower in South Yarra, despite Stonnington Council's preferred heigh limit of 13 storeys.

Public Transport Minister Jacinta Allan said Mr Davis was a "loose cannon" who was threatening jobs and investor confidence.

"The Liberals spent four years selling Melbourne's skyline to the highest bidder, and now they want to play petty politics with a vital project that delivers safer streets, more trains and new homes," she said.

Ms Allan also took a swipe at the Greens, accusing the party of making a "complete mockery of their own manifesto to see more Victorians using public transport".

Glen Eira mayor Mary Delahunty??? said the council engaged experts to decide on the appropriate type of building for the area, and while she believed it would still be too high, the community now wanted certainty.

"It would be disappointing if we see this drag on any longer, and still have the same outcome. It is being used as a political football and that's not fair to the residents, they need to know what's going on in their neighbourhood," she said.

The development will have street-level retail, and office and apartments above the station that was revamped under the government's signature $6.9 billion level crossing removal project.