Health authorities have warned there is "clearly some activity" happening around Ararat after traces of coronavirus were detected in wastewater.
As a result, a pop-up testing site has been set up at East Grampians Health Service on Girdlestone Street, from 9.30am on Friday.
The site will be open across the whole of the long weekend.
Victoria's commander of testing and community engagement Jeroen Weimar encouraged Ararat residents to get tested to help authorities establish whether there was a new case in the area.
"We clearly have some activity happening in the Ararat area. We're very keen to identify whether this is an old case, or whether this is a new case that's developing," he said.
"What the surveillance testing identifies for us is a warning sign that says that either somebody has traveled through the area who has been shedding the virus. It may be an old case in the community. It may be someone who has come back from another part of the state. Or, it may be a new case.
"At this point, it's a reminder that we're not free of the virus. We continue to have this exposure to all of our communities and it's important we listen to these early warning signs."
"We've seen a great community response from these kind of traces and these early warning signs that there might be something afoot," Mr Weimar said.
"We tested around 15% of the population in both Anglesea and Appollo Bay. We, in the end, did not find a definitive case of coronavirus.
"We'd like to make sure that we that we run this one to ground as quickly as we did in those other two localities."